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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLTCL1
All Species:
13.64
Human Site:
S376
Identified Species:
25
UniProt:
P53675
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53675
NP_009029.3
1640
187030
S376
N
T
L
F
A
Q
G
S
Y
A
E
A
A
K
V
Chimpanzee
Pan troglodytes
XP_001154119
1640
186911
S376
N
T
L
F
A
Q
G
S
Y
A
E
A
A
K
V
Rhesus Macaque
Macaca mulatta
XP_001108544
1639
187872
N376
N
A
L
F
A
Q
G
N
Y
S
E
A
A
K
V
Dog
Lupus familis
XP_534763
1673
189990
S376
S
T
L
F
A
Q
G
S
Y
A
E
A
A
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q68FD5
1675
191538
N376
N
A
L
F
A
Q
G
N
Y
S
E
A
A
K
V
Rat
Rattus norvegicus
P11442
1675
191580
N376
N
A
L
F
A
Q
G
N
Y
S
E
A
A
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509659
1675
191558
N376
N
A
L
F
A
Q
G
N
Y
S
E
A
A
K
V
Chicken
Gallus gallus
XP_415060
1672
190998
S376
N
T
L
F
A
Q
G
S
Y
A
D
A
A
K
V
Frog
Xenopus laevis
NP_001085860
1675
191412
N376
N
A
L
F
A
Q
G
N
Y
S
E
A
A
K
V
Zebra Danio
Brachydanio rerio
XP_699126
1677
191618
N376
N
N
L
F
A
G
G
N
Y
S
E
A
A
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29742
1678
191159
Q376
N
K
L
F
T
A
G
Q
Y
A
E
A
A
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34574
1681
191524
Q374
N
L
L
F
S
N
G
Q
F
G
E
S
A
K
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22137
1653
187216
D382
E
S
L
L
L
Q
N
D
Y
Q
N
A
A
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
84.6
90.6
N.A.
83
82.9
N.A.
82.9
88.1
82.5
83.3
N.A.
75.3
N.A.
67.8
N.A.
Protein Similarity:
100
99.6
93.2
94.8
N.A.
91.5
91.4
N.A.
91.3
93.9
91.2
91.1
N.A.
87
N.A.
82.1
N.A.
P-Site Identity:
100
100
80
93.3
N.A.
80
80
N.A.
80
93.3
80
73.3
N.A.
73.3
N.A.
53.3
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
93.3
100
93.3
86.6
N.A.
73.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
69.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
0
0
77
8
0
0
0
39
0
93
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
85
0
0
0
0
% E
% Phe:
0
0
0
93
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
93
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
100
0
% K
% Leu:
0
8
100
8
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
85
8
0
0
0
8
8
47
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
77
0
16
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
8
0
0
31
0
47
0
8
0
0
0
% S
% Thr:
0
31
0
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _